My 13 year old dog is on potassium bromide for seizures. Will her heartworm medicine and oral flea medicine interfere
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Great question! As far as actual drug interactions, there is no concern with administering potassium bromide with any oral or topical heartworm or flea/tick preventatives. Some oral flea and tick preventatives (such as Nexgard and Comfortis/Trifexis) state to administer with caution in dogs with a history of seizures. That said, these results come from a controlled studies where several of the dogs had a history of seizures prior to the administration of these medications.
On a personal side note, I give my own 10 year old dog Nexgard and Heartgard as well as potassium bromide for seizure control without hesitation. I do not feel that the studies are controlled well enough to indicate a causal relationship between Nexgard and seizure activity. That said, if you have major concerns, you can always use a topical flea/tick preventative, such as Advantix.
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