Is there a difference between topical and tablet heartworm and fea/tick medicines when it comes to how it works in the body? Is it correct that heartworm medicine needs to make it to the blood stream and the flea/tick medicine needs to stay at the surface? Which is safer/less toxic for the dog? Is it beneficial to separate the timing of administration of heartworm prevention and tick/flea prevention to not overload the body at once?

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